This area of the site gives SIGN’s recommendations for treatment of acute, chronic and advanced HCV. There are also notes on working with children and mothers, and the role of nutrition, supportive care and complementary therapies.

Acute hepatitis C

Information on the natural history of acute hepatitis C and post-exposure prophylaxis, plus recommendations on timing, choice and duration of treatment.

Treatment of chronic hepatitis C

Information on antiviral therapy, effectiveness, contraindications, management of adverse effects, relapse or failed treatment and monitoring of patients not receiving treatment. Plus a quick reference guide to treatment of chronic HCV.

Treatment of advanced infection

Guidance on antiviral therapy for patients with cirrhosis and those referred for liver transplant, criteria for liver transplantation and screening for hepatocellular carcinoma.

Treatment of children with hepatitis C

Notes and guidance on treating children with HCV.